Until now, you You may see "exosomes" surfaced on your page, perhaps sandwiched between the promo code for snail mucin and the promo code for rendering beef cattle. Scroll through Skintok long enough that you will run into a lot of videos to hype exosome therapy, external serum and exosome therapy are expected to keep Cherub's skin healthy.
The skin care company has seized the semester. Sold as a miraculous regeneration agent, you'll find them in a $300 facial menu, post-muscular sequence program, and a skin care program across the influencers.
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Exosomes are small sacs inside cells, or what scientists might call extracellular vesicles. They act as cell membranes, through which small bags of cell from one cell to another, bringing the function of mRNA, lipids and other genetic materials.
Exosomes are part of the human internal message system, which regulate everything from cell growth to hormone production and gene expression. They are microscopes that measure about 40 to 100 nanometers, so the red blood cells appear large by comparison. Scientists first discovered them under microscopes in the 1960s, but they didn't get much attention until the early 2000s.
In medicine, exosomes are being studied for cancer therapy, neurodegenerative diseases and drug delivery systems. Because they reflect the state of the cells in which they originate, cancer cells usually release exosomes containing unique molecular fingerprints. Scientists are already using these biomarkers to help diagnose diseases such as prostate cancer in the early stages. The potential for early noninvasive testing in a range of diseases is great.
Since exosomes can cross biological barriers and provide cargo, the researchers also explored them as vehicles of target drugs. Furthermore, they have the potential to heal wounds, reduce inflammation and tissue regeneration.
Naturally, the beauty industry has captured the wind. Now, exosome moisturizers, serums and hair injections are expected to repair the skin barrier, enhance collagen production and reverse aging.
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But this is a dark place. Most clinical studies on exosome skin care are small-scale or lack strict controls. Unlike drugs, exosomes have no fixed components, no standardized doses, and lack good manufacturing practices (GMP). This variant makes the patient's prognosis difficult to predict. Their contents may be transferred from batch to batch. Sources from mesenchymal stem cells (MSCs) and platelets to plant cells and umbilical cord tissue also vary.
“Not all exosomes are the same,” said Jodi Gurney, co-founder of Exotropin. “The source, production process and goods determine their effectiveness.”
“There is no technology yet that allows manufacturers to place exosomes into bottles, place them on racks, and prevent them from degrading,” said Jimmy Sung, a board-certified plastics and reconstruction surgeon, specializing in regenerative aesthetics. "Even if they say, 'We put in X quantities,' there is no way to verify how much remains active. They won't be able to take the oath in writing or testify."
If the company purifies exosomes into drug-grade standards, it needs to be classified as a drug. Many people combine them with traditional skin care ingredients such as hyaluronic acid or vitamin C to make it work together. This also means that if the consumer notices positive results, it may be due to additives (rather than so-called exosomes).
Exosomes are not living cells, so they have less risk than stem cell therapy. Nevertheless, they are biologically active, meaning pollution is a serious problem. Improper purification can lead to products containing unnecessary goods: viral miRNAs, immunosuppressants and tumor growth factors (to name only).
“I personally avoid using non-automatic exosomes in my practice unless I can thoroughly review the origins, safety data and mechanisms of action of the product,” Hannah Kopelman, a dermatologist specializing in hair and scalp diseases, wrote in an email. “The U.S. Food and Drug Administration (FDA) has issued a warning about the abuse of unapproved exosome products, and as a practitioner, it can cause red flags. Unless I have complete confidence, I cannot use products that I would not use for myself or my own family.”