Universal Music Group fought back last year when Drake tried to sue the group over the release of Kendrick Lamar's diss track "Not Like Us."
The Canadian musician filed a lawsuit on Tuesday, accusing the company of defamation by allowing the song to be published and claiming it spread a "false and malicious narrative" that he was a pedophile.
In response, Universal, which has been Drake's record label for more than a decade, said: "Not only are these claims untrue, but the idea that we are trying to damage the reputation of any artist — let alone Drake — is inappropriate. Logical."
It also accused the star of trying to "silence" Lamar by taking their rap battle to court.
The label said: "Throughout his career, Drake has intentionally and successfully used Universal Music Group to spread his music and poetry in traditionally outrageous back-and-forth 'rap battles' to express his Feelings about other artists.”
"He now seeks to weaponize the legal process to suppress an artist's creative expression and seek damages from (Universal) for distributing that artist's music."
In response to claims that Universal deliberately harmed Drake's career, the label noted that it has "invested significantly" in his music, helping him "achieve historic commercial and personal financial success."
"We have not, and will not, defame any individual," the statement concluded.
Drake's lawsuit, filed Wednesday in New York, marks the latest chapter in his long-running feud with Lamar.
The pair clashed over a series of rap songs last year. In one of the letters, Drake accused Lamar of domestic abuse. Lamar responded with "Not Like Us," in which he described Drake and his entourage as "certified pedophiles" who should be "registered and placed on neighborhood watch."
In court documents, Drake claims Universal knew Lamar's lyrics were fake but "continued to fan the flames" of the controversy for profit.
He claimed the label used the song to launch "a viral campaign" and suggested the shooting at his Toronto mansion last May was directly related to those actions.
He said Universal "chose corporate greed over the safety and well-being of its artists."
However, the legal case is not against Lamar himself.
"This lawsuit has nothing to do with the artist who created 'Not Like Us,'" the court filing said.
"Rather, this is entirely about Universal Music Group, a music company that decided to publish, promote, exploit and profit from allegations that it believes are not only false but dangerous."