The Best Ergonomic Mouse (2025), Testing and Reviewing

Other ergonomic mice should consider

Photo: Henri Robbins

KeyChron M6 costs $50: If you like the design of the MX Master series but want to use a more gaming-oriented mouse, the KeyChron M6 is a great choice. While the M6 ​​doesn't have Logitech's advanced gesture controls or soft touch exterior, it keeps dual-mode scroll wheels, horizontal wheels and general ergonomics while adding 4,000 Hz refresh rate and reducing the 3s by almost half to just 78 grams. However, the build quality and loss of functionality of some minor issues make this less than ideal for most users - the dual-mode wheel rattles during use and the mouse feels lightweight to the malfunction. A wireless receiver for a high-performance model requires a USB-C cable to connect to the device, which is much less convenient for laptop users than the 1,000-Hz model (and most other mice today) (and most other mice).

Photo: Henri Robbins

KeyChron M4 costs $50: While you can actually transport any mouse on this list in a backpack or computer bag, I was impressed by the compactness of the keychain M4. Without any problems, I could easily slide it into my laptop bag or jacket pocket and even use it as a travel mouse for quite some time. Although the shape is not very good, or even good, in terms of ergonomics, I found that the claw grips were also comfortable during long play. But unless I hope the lightest mouse will be able to use the lightest mouse, I would recommend it to anyone who uses it every day is not good enough. My only real complaint about this mouse is the dongle: the 4,000-Hz model comes with a keypad-like receiver with a USB-C port on the back, which means I need a cable to connect the receiver and the flat surface to place it. Meanwhile, the 1,000 Hz model comes with a simple USB dongle that can be plugged into the side of the laptop.

Logitech Pro X Superlight 2 Dex priced at $180: Although the mouse is designed for high-strength competitive games, I found its engraved shape to be practical and comfortable, available for any long-term use, and its lightweight (60g!), the ripped steel design is fast and lively for spreadsheets and shooters. Despite its weight, the mouse feels very solid, and the 8-kHz vote combined with the 44K-DPI sensor makes it the best performing mouse on this list. While expensive, Superlight Dex is a great bike solution for those who work from home and start queuing right after the elimination. It's more gaming-centric lean than the Razer Basilisk V3, which isn't bad, meaning you make more sacrifices for productivity in exchange for gaming performance.

Photo: Henri Robbins

Logitech MX vertically priced at $120: While this mouse is both size and general shape suitable for regular use, I find this shape a little uncomfortable when fully grasped and lifted: a prominent ridge on the back dug into the space between my thumb and index finger, and the shape is a bit narrow and cannot be fixed well. However, the MX's vertical distance still holds loose grips and is very useful for general office work and browsing compared to a standard horizontal mouse, while making less stress on the wrist.

Photo: Henri Robbins

Logitech Lift, priced at $80: As one of the smaller vertical mice on this list, the elevator is a little too small. I found it difficult to comfortably grab this mouse for long use, and friends with smaller hands found the same purpose. That being said, Wired Review editor Julian Chokkattu said his 5'2" wife used life and found it perfectly suited her small hands, so your mileage would be different. No matter the hand-made size, a larger vertical mouse is usually more comfortable. For most people, it's worth mentioning. The lift is one of the only vertical mice I have for the left-hand configuration.


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