Research says

American researchers say mosquito drugs should be removed from malaria drugs so that the disease can no longer be transmitted.

Malaria parasites kill nearly 600,000 people each year, mainly children, and are transmitted by female mosquitoes when drinking blood.

Current efforts are aimed at killing mosquitoes with insecticides, rather than curing malaria.

But a team at Harvard University discovered a pair of drugs that can successfully eliminate malaria insects when their legs absorb. Paint bed nets in drug cocktails are long-term goals.

Sleeping under the net of the bed has always been one of the most successful ways to prevent malaria, as the main mosquitoes that spread malaria at night.

Vaccines are also recommended to protect children living in areas with high-risk malaria.

Mosquito nets are both physical barriers and contain insecticides that kill mosquitoes.

But mosquitoes are already resistant to insecticides in many countries, so chemicals are no longer as effective as they used to kill insects.

"Before that, we didn't really try to kill the parasites in mosquitoes directly because we just killed mosquitoes," said Alexandra Probst, a researcher at Harvard University.

But, she said the method “no more cut it.”

The researchers analyzed the DNA of malaria to find potentially weak spots, while it was infecting mosquitoes.

They narrowed a large number of potential drug libraries to the shortlist of 22. The drugs were tested when female mosquitoes were contaminated by malaria.

Scientists describe two highly effective drugs in their articles in nature that kill 100% of parasites.

These drugs were tested on materials similar to bed nets.

"Even if the mosquitoes survive with the bed net, the parasites inside are killed, so it still doesn't spread malaria," Dr. Probst said.

“I think it’s a very exciting approach because it’s a whole new way to target the mosquito itself.”

She said malaria parasites are unlikely to be resistant to drugs, as there are billions of dollars per infected person, but fewer than five per mosquito.

The effects of these drugs lasted for a year on the net, which could make them a cheap and lasting alternative to pesticides, the researchers said.

This method has been demonstrated in the laboratory. The next phase has been planned in Ethiopia to see if the anti-malarial bed network is effective in the real world.

It will take at least six years for all studies to complete to know if this approach works.

However, the vision is to treat the bed net with both anti-Malaria drugs and pesticides so that if one method does not work, another method will.