Jerusalem - Just hours after President Donald Trump ended his visit to the Middle East, Iran's Ayatollah Ali Khamenei launched a long war against the United States and Israel on Saturday, accusing Trump of being a liar and calling for the destruction of the Jewish state.

Khamenei on X added on X: "Trump said he wanted to use his power to achieve peace. He was lying.

Since the 1980s, Washington has designated Iran as a state sponsor of terrorism. Fanatic anti-Western and anti-Semitism Ayatollah called the Jewish state - a key US ally in the Middle East - a "cancer tumor" that must be uprooted.

According to the Trump administration, Khamenei's regime is the world's leading initiator of anti-Semitism.

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Khamenei also targets Sunni Arab countries that have allied with the United States Middle East, including Saudi Arabia and Qatar.

“This failed pattern, without the support of the United States, Arab countries were told that they could not survive for ten days.

The sly 86-year-old revolutionary Islamist said Washington aims to promote Sunni Arabs’ dependence on Washington. “The United States hopes these countries can’t do without it – that’s the message they’re doing and the proposal.”

Khamenei also accused the United States of using its resources to attack Hamas-controlled Gaza Strip.

"The United States has used its massacre in Gaza to carry out wars as much as possible and to arm mercenaries," Khamenei said. Hamas, the designated terrorist movement in the United States, is a strategic partner of the Iranian regime. Hamas invaded Israel on October 7, 2023 and massacred more than 1,200 people, including many Americans.

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During a trip to Saudi Arabia, the United Arab Emirates and Qatar, Trump called the Iranian regime a major force in instability in the Middle East.

"The biggest and most destructive of these forces is the Iranian regime, which has caused unimaginable suffering in Syria, Lebanon, Gaza, Gaza, Iraq, Yemen and other regions," Trump said in the Kingdom of Saudi Arabia.

Alireza Nader of Washington, DC, an expert in the Iranian regime, told Fox News Digital that Iran “has suffered a serious setback from Israel and the Iranian public wants the regime to be overturned. President Trump has an overwhelming advantage in negotiations and can severely limit and limit the regime’s nuclear program.”

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Trump said he hopes to reach a deal with Iran to block its illegal nuclear weapons program. In his speech, Trump told Iran that it must give up the momentum to build an atomic bomb.

"When you build the world's tallest skyscrapers in Jeddah and Dubai, the landmark in Tehran collapsed in 1979," Trump said. "The corrupt water mafia (of Iran) ... caused drought and empty riverbeds. They got rich."