After the historic announcement that Robert Francis Prevost, 69, of Chicago, was appointed as the new pope, exploded with humor and Chicago pride on Thursday.

Now known as Pope Leo XIV, Prevost has become the first pastor in the United States to lead the Roman Catholic Church, ending the Vatican's long-standing opposition to the idea of ​​the American pope.

The response quickly drowns out social media platforms like X and Bluesky, with Chicago and Americans all over the country chatting and sharing jokes.

Chicago Mayor Brandon Johnson celebrated the moment on social media, saying: "Everything, including the Pope, is from Chicago! Congratulations to the first American Pope Leo XIV! We hope to welcome you home soon."

Other users asked for "photos of the new pope in the famous Chicago sculpture", while MSNBC's Chris Hayes wanted to know if the pope was a fan of the Chicago Cubs, while others asked if he was a White Sox fan.

One X user joked: "In honor of Chicago's own Pope Leo XIV, the White Sox announced a new "White Smoke Milkshake" that will be delivered in a hat commemorating the Pope." Another sneer on the Chicago Bears American football team, wrote: "Chicago produced the Pope before QB threw a 4,000-yard QB."

Others mentioned Chicago's famous deep-dish pizza, joked that the Pope provided pizza for it and asked if the new pope thought there were better pizza in Chicago or Rome.

One commenter wrote: “From now on all the communion Vakinf will be deep plates.” Another added: “Deep plate Eucharist”, another user joked: “End of the day Rome will have good pizza.”

There was also a nod to the city's infamous liqueur, and some asked the Pope if he had consumed Malört, the liqueur that was once reserved for the Chicago diving bar.

One user wrote: “Can’t wait to replace holy water and wine with malat and old style.”

Also mentioned are Bears, Emmy Award-winning Chicago drama, and the city’s groundbreaking and legendary comedy club Second City, one user noted that “the second city is now second only to Vatican City.”

Some also joked that Pope Leo XIV "maybe more hot dogs than all 266 previous Pope combinations."

The social media accounts associated with the New York Knicks also celebrated that the new pope, a Villanova graduate, wrote: "Villanova graduates are a weeklong week," which included photos of the pope and Knicks players Jalen Brunson, Josh Brunson, Josh Hart and Mikal Bridges, who are also Villanova alumni. The New York basketball team won the first two games against the Boston Celtics in the playoffs.

Business accounts have also been added. Fried chicken chain Popeyes released “Pope Yes” while Netflix shared All Dill from Emily, Paris, with the title: “I’m from Chicago, but I moved here to find a job.”